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https://www.selleckchem.com/pr....oducts/Cyclopamine.h
In vivo, polyphenols reduced cerebral infarct volume and hemorrhagic transformation aggravated by hyperglycemia. Polyphenols attenuated redox changes, increased VE-Cadherin production and decreased neuro-inflammation in infarcted hemisphere. Conclusion Polyphenols protected against hyperglycemia-mediated alterations in cerebral endothelial cells and a mouse stroke model. It will be relevant to assess polyphenol-based strategies to improve cerebrovascular damage and stroke recovery during diabetes. This article is protected by copyri