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Examining the mechanisms of HCMV immune escape really helps to discover strategy to inhibit HCMV replicate. CD8+ T cells perform a critical part in the resistant response to viral pathogens. However, the mechanisms of HCMV to avoid the attack by CD8+ T cells remain largely unidentified. Viral CXCL1 (vCXCL1) is the production of HCMV UL146 gene. Right here, we found that vCXCL1 promoted the resistance of hepatic cells to CD8+ T cells. vCXCL1 increased the
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