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We investigated the efficacy and tolerability of gabapentin for treating menopausal hot flushes via a meta-analysis. TECHNIQUES We searched the PubMed, MEDLINE, EMBASE, and CENTRAL databases for English-language articles published until June, 2018. The following search phrases were used "menopause," "hot flushes," "vasomotor symptoms," "gabapentin," and "non-hormonal treatment." Major results were frequency, duration, and composite score of hot flushes. Secondary outcomes were undesireable e